RNA sequencing-based approaches in drug discovery

“Shaping a World-class University”
Master Degree in Pharmaceutical Biotechnologies University of Padova

Caterina Carraro, PhD
Institute for Stroke and Dementia (ISD) di Ludwig-Maximiliens-Universität (LMU) München German Center for Neurodegenerative Diseases (DZNE) | Systems Medicine, Bonn

The SC structure will include both interactive multidisciplinary seminars and hands-on bioinformatics sessions.

Students will gain knowledge on the basics of sequencing-based omics, on how to approach a single-cell transcriptomic analysis and their diverse applications in the drug pipeline, enlarging their knowledge on the use of sophisticated multi-omics techniques in drug discovery.

*MANDATORY REGISTRATION (for complete Short Course including Lectures, workshop, test)
BEFORE NOV. 25, 2025 @ https://bit.ly/RNACOURSE-CARRARO-JAN26

Lecture 1 Wed, January 7, 2026, 14:00-16:00 @Aula 2 DSF
Fundamentals of Transcriptomics

• - Sequencing-based omics in a nutshell: definition and complementarity with reductionist approaches
• - Transcriptomics and Epigenomics: overview of the major bulk and single-cell technologies
• - Examples and rationale for the selection of the most suited omics approach in your research

Lecture 2 Thu, January 8, 2026, 14:00-16:00 @Aula 2 DSF
Omics-driven experimental and computational approaches in Drug Discovery

• - Experimental platforms for the omics-based screening of drug candidates and MoA characterization
• - Bioinformatic tools and pipelines to support omics-based drug discovery and repurposing

Workshop Fri, January 9, 2026, 9:00-13:00, @AID (mandatory registration*, limit: 24 students)
Introduction to single-cell data analysis

• - Bioinformatics tutorial: tackling single-cell transcriptomics data with the open-source processing pipeline Seurat

Venue

Aula 2 and Aula Informatica Didattica (AID) of the Dipartimento di Scienze del Farmaco, via Marzolo 5, Padova

Credits for Pharmaceutical Biotechnologies students

2 CFU as Short Course “In depth analysis…” can be obtained only upon PASSED score at the final test.

Final test

Multiple choice test on the Moodle of the course (Please note that in presence attendance to all lectures and workshop is required to access the test and obtain the credits)

*MANDATORY REGISTRATION (for complete Short Course including Lectures, workshop, test)
BEFORE NOV. 25, 2025 @ https://bit.ly/RNACOURSE-CARRARO-JAN26

Info

barbara.gatto@unipd.it
alice.sosic@unipd.it