Lisa Dalla Via
Department of Pharmaceutical and Pharmacological Sciences, University of Padova Position: Associate Professor of Medicinal Chemistry (SSD CHIM/08) Contacts |
Short CV
Lisa Dalla Via achieved the Degree in Biological Sciences with full marks cum laude in March, 1989 at the University of Padova. In 1990 achieved the Board Certified in Biological Sciences. In 1990 and 1991 she carried out research activity owing to a grant from Sigma-Tau (Roma). She obtained the PhD in Biochemistry and Biophysics in 1995. From 1994 she joined the Department of Pharmaceutical Sciences, Researcher of Medicinal Chemistry of the Faculty of Pharmacy of the University of Padova from 2002 and associate professor from 2010. She is supervisor of a number of degree thesis in Pharmaceutical Sciences and of two PhD thesis of the PhD School in Molecular Sciences. She is principal investigator of the Research Programs "ex 60%" and of a Scientific Project inside "Progetti di Ricerca di Ateneo-anno 2010".
She is author of 88 scientific papers published in international journals and many abstracts at national/international meetings.
Teaching
Office hours
by appointment
Availability for Thesis Projects
Mechanism of action of novel antitumor drugs
Research
Scientific Activities
The research activity, in collaboration with national and international research groups, deals with: a) the study of the mechanism of transport and action of polyamines in rat mitochondria isolated from liver or heart; b) the study of the mechanism of action of natural and synthetic compounds: effect on normal and tumor cells; c) the study of the interactions between natural or synthetic compounds and cellular targets.
Reviewer for the following international journals: Archives of Dermatological Research, Journal of Photochemistry and Photobiology B: Biology, Bioorganic & Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, European Journal of Medicinal Chemistry, Tetrahedron Letters, Journal of Natural Products and Journal of Biological Inorganic Chemistry. Visiting professor at the Tokyo University of Science in December 2008. She received three financial supports inside the "Iniziative di Cooperazione Universitaria-anno 2012" and "Iniziative di Cooperazione Universitaria-anno 2014" for a cooperation with the Universidad Nacional Autonoma de Mexico and "Iniziative di Cooperazione Universitaria-anno 2015" for a cooperation with the Universidad de Colima (Mexico)
Publications
L. Dalla Via, A. N. García-Argáez, M. Martínez-Vázquez, S. Grancara, P. Martinis, A. Toninello
Mitochondrial permeability transition as target of anticancer drugs
Curr. Pharm. Des. 20, 223-244 (2014)
L. Dalla Via, G. Marzaro, A. Mazzoli, A. Chilin, G. Miolo
Photobiological properties of 3-psoralenacetic
acids
Photochem. Photobiol. Sci. 14, 2074-2086 (2015)
M.S. Christodoulou, F. Calogero, M. Baumann, A.N. García-Argáez, S. Pieraccini, M. Sironi,F. Dapiaggi,R. Bucci, G. Broggini, S. Gazzola, S. Liekens, A. Silvani, M. Lahtela-Kakkonen, N. Martinet, A. Nonel-Canals, E. Santamaría-Navarro, I. R. Baxendale, L. Dalla Via, D. Passarella
Boehmeriasin A as new lead compound for the inhibition of Topoisomerases and SIRT2
Eur. J. Med. Chem. 92, 766-775 (2015)
L. Dalla Via, M. Mejia, A. N. García-Argáez, A. Braga, A. Toninello, M. Martínez-Vázquez
Anti-inflammatory and antiproliferative evaluation of 4b-cinnamoyloxy,1b,3a-dihydroxyeudesm-7,8-ene from Verbesina persicifolia and derivatives
Bioorg. Med. Chem. 23, 5816-5828 (2015)
S. Salerno, A. M. Marini, G. Fornaciari, F. Simorini, C. La Motta, S. Taliani, S. Sartini, F. Da Settimo, A. N. García-Argaez, O. Gia, S. Cosconati, E. Novellino, P. D'Ocon, A. Fioravanti, P. Orlandi, G. Bocci, L. Dalla Via
Investigation of new 2-aryl substituted benzothiopyrano[4,3-d] pyrimidines as kinase inhibitors targeting vascular endothelial growth factor receptor 2
Eur. J. Med. Chem. 103, 29-43 (2015)
Research projects and Funds
2011 - 2015: Ex 60% Projects, University of Padova, - PI.
Mechanism of action of antiproliferative drugs.
2008 – 2009: Research Grant, 37.596 euro - PI.
Biological activity of active principles isolated from plants used in folk Mexican medicine.
2011-2013: PRAT-2010, 36.150 euro – PI.
Antitumor activity of novel coordination compounds on non-small cell lung cancer (NSCLC).
2006-2007: PRIN-2006, MIUR - Italian Ministry of Scientific Research, 49.000 euro - P.
Synthesis and evaluation of dual topoI/II inhibitors and protein kinase CK2 inhibitors.
