Stefano Moro
Direttore del Dipartimento di Scienze del Farmaco
 | Molecular Modeling Section (MMS) Department of Pharmaceutical and Pharmacological Sciences, University of Padova Contacts Lab Web Page: http://mms.dsfarm.unipd.it |
Short CV
Stefano Moro is the principal investigator of the Molecular Modeling Section (1999 – present) of the Pharmaceutical Sciences Department, and in 2011 was appointed as Full Professor in Medicinal Chemistry of the University of Padova, Italy. The Molecular Modeling Section (MMS) constitutes the interface among biological/pharmacological and chemical laboratories in our Department, adding its computational expertise as needed in organic synthesis, phytochemistry, biochemistry, molecular biology and pharmacology.
Bibliographic Sketch:
Dr. Moro received his M.S. degree in Medicinal Chemistry (1991) from University of Padova (Italy) and Ph.D. degrees in Physical Organic Chemistry (1995) with Prof. Fulvio Di Furia at University of Padova. Following his doctoral studies, he was Fogarty Postdoctoral Associate with Dr. Kenneth Jacobson in the Molecular Recognition Section, National Institute of Diabetes, Digestive, and Kidney Diseases, of the National Institutes of Health in Bethesda (MD, USA), before joining again the University of Padova in 1999 as Assistant Professor. In 2003, Dr. Moro was invited as Visiting Professor at the School of Pharmacy of the ETH of Zurich, Switzerland. From December 2011, he has been appointed as Full Professor of Medicinal Chemistry at the University of Padova.
He has authored or co-authored more than 200 original research papers and 2 international patents.
Dr. Moro is also the recipient of several national and international awards (January 1998: N.I.H. Fellow Award for Research Excellence; May 2000: Federchimica National Award for Research Excellence in Chemistry; September 2002: Farmindustria National Award for Research Excellence in Medicinal Chemistry.
His name was recently included in the VIA-Academy Top Italian Scientists.
The complete CV can be downloaded following this web address:
http://mms.dsfarm.unipd.it/files/CV/SMoro_CV.pdf
Teaching
Research
Scientific Activities
GPCRs - Adenosine Receptors | |
Topic hints: | G protein-coupled receptors (GPCRs) represent the largest family of signal-transducing molecules known. They convey signals for light and many extracellular regulatory molecules. GPCRs have been found to be dysfunctional/dysregulated in a growing number of human diseases and have been estimated to be the targets of more than 40% of the drugs used in clinical medicine today. The crystal structures of several GPCRs support both homology modeling studies and structure-based drug design approaches. Our scientific efforts are directed on adenosine receptors, We will place the greatest emphasis on an iterative, bi-directional approach in which models are used to generate hypotheses that are tested by experimentation and the experimental findings are, in turn, used to refine the model. The success of this approach is due to the synergistic interaction between theory and experiment. |
Collaborators: | Giampiero Spalluto's group |
