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Recent publications, available positions, etc.
Polymer conjugation to prevent biological barrier crossings
Dodd A, Natfji AA, Evangelinos A, Grigoletto A, Pasut G, Beards F, Renshall L, Osborn HMI, Greco F, Harris LK. Conjugation to PEG as a Strategy to Limit the Uptake of Drugs by the Placenta: Potential Applications for Drug Administration in Pregnancy. Mol Pharm. 2022;19(1):345-353. doi: 10.1021/acs.molpharmaceut.1c00498
PEG-Hyaluronic acid Hydrogels
Saggioro M, D'Agostino S, Gallo A, Crotti S, D'Aronco S, Corallo D, Veltri G, Martinez G, Grigoletto A, Tolomeo AM, Tafuro G, Agostini M, Aveic S, Serafin V, Semenzato A, Pasut G, Pozzobon M. A rhabdomyosarcoma hydrogel model to unveil cell-extracellular matrix interactions. Biomater Sci. 2021;10(1):124-137. doi: 10.1039/d1bm00929j.
Comment on impact of anti-PEG Abs in COVID-19 nano-vaccines
Bigini P, Gobbi M, Bonati M, Clavenna A, Zucchetti M, Garattini S, Pasut G. The role and the impact of polyethylene glycol on the anaphylactic reactions to the COVID-19 nano-vaccines. Nat Nanotech. 2021;16(11):1169-1171. doi: 10.1038/s41565-021-01001-3.
Targeted Anticancer Conjugate
Grigoletto A, Martinez G, Gabbia D, Tedeschini T, Scaffidi M, De Martin S, Pasut G. Folic Acid-Targeted Paclitaxel-Polymer Conjugates Exert Selective Cytotoxicity and Modulate Invasiveness of Colon Cancer Cells. Pharmaceutics. 2021;13(7):929. doi: 10.3390/pharmaceutics13070929.
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